TELFAST 120/MG TAB 15/TAB

Indications

Approved Uses

Seasonal allergic rhinitis, chronic idiopathic urticaria

Dosage & Administration

Dosing by Condition

Seasonal Allergic Rhinitis (Adults and children ≥12 years): 120mg once daily or 60mg twice daily
Chronic Idiopathic Urticaria (Adults and children ≥12 years): 180mg once daily or 60mg twice daily]

Initial Dose

120mg once daily for allergic rhinitis

Maintenance Dose

120mg once daily

Maximum Dose

180mg once daily for adults and children 12 years and older

Childrens Dosage

Seasonal Allergic Rhinitis (2 to 11 years): 30mg twice daily. Chronic Idiopathic Urticaria (6 months to 11 years): 15mg twice daily for 6 months to <2 years; 30mg twice daily for 2 to 11 years.

Dose Adjustment Notes

Renal impairment: consider a reduced starting dose (commonly 60 mg once daily) in decreased renal function; no routine adjustment is needed for hepatic impairment; elderly may require caution mainly due to renal function.

How to Take

Swallow the 120 mg film‑coated tablet whole with water; avoid taking with fruit juices (apple/orange/grapefruit).

Side Effects

Common Side Effects

Headache, drowsiness, nausea, dizziness, fatigue, dry mouth

Side Effect Frequency

Common: headache, nausea, dizziness (and sometimes fatigue/somnolence reported at low rates). Less common/rare: hypersensitivity reactions including rash/urticaria/angioedema/anaphylaxis; palpitations/tachycardia are uncommon.

Safety & Warnings

Contraindications

Hypersensitivity to fexofenadine hydrochloride or to any excipients in the product.

Warnings & Precautions

Use caution in renal impairment; avoid/limit fruit juices (apple/orange/grapefruit) around dosing due to reduced absorption; seek medical advice if you have significant heart disease or develop hypersensitivity symptoms.

Age Restriction

TELFAST 120 mg tablets: for adults and adolescents ≥12 years; not recommended/indicated for children <12 years (use age-appropriate fexofenadine formulations/doses).

Driving Warning

May Cause Drowsiness

Drug Interactions

Drug Interactions

Antacids containing aluminum/magnesium: reduce absorption (separate by ~2 hours); erythromycin and ketoconazole: increase fexofenadine exposure; fruit juices (apple/orange/grapefruit): reduce bioavailability-avoid or separate.

Interaction Severity

MODERATE: aluminum/magnesium-containing antacids (separate by ~2 hours). MODERATE: erythromycin and ketoconazole (increase fexofenadine exposure but usually without serious clinical consequences). MODERATE (clinically relevant): fruit juices (decrease absorption/efficacy).

Food Interaction

Avoid fruit juices (apple/orange/grapefruit) around dosing; take with water (food may modestly affect absorption but the clinically important interaction is with fruit juice).

Alcohol Interaction

Avoid

Special Populations

Children

Seasonal Allergic Rhinitis (2 to 11 years): 30mg twice daily. Chronic Idiopathic Urticaria (6 months to 11 years): 15mg twice daily for 6 months to <2 years; 30mg twice daily for 2 to 11 years.

Elderly

Standard adult dosing, but start at the lower end of the dosing range (60mg daily) as they may be more sensitive to effects.

Kidney Impairment

For this 120 mg tablet (≥12 years): in renal impairment, start with 60 mg once daily (use a lower-strength product); no adjustment needed in normal renal function.

Storage & Patient Advice

Missed Dose

Take the missed dose as soon as remembered; if it is close to the next dose, skip the missed dose and resume the regular schedule; do not double doses.

Stopping the Medicine

Safe to stop anytime

Overdose

Symptoms may include dizziness, drowsiness/fatigue, and dry mouth; manage with symptomatic/supportive care (consider decontamination if recent ingestion); hemodialysis is not effective-seek urgent medical attention.

Patient Counseling

Take once daily with water; avoid apple/orange/grapefruit juice; separate aluminum/magnesium antacids by ~2 hours; usually non‑drowsy but use caution with driving until you know your response; seek urgent care for signs of hypersensitivity (e.g., facial/lip/tongue swelling, breathing difficulty).

Monitoring Requirements

No routine monitoring

Pharmacology

Mechanism of Action

Selective peripheral H1‑receptor antagonist that blocks histamine-mediated symptoms with minimal CNS penetration (low sedation).

Onset of Action

1-3 hours

Duration of Effect

12-24 hours

Half-Life

14.0 to 18.0 hours in healthy adults

Metabolism

Minimal metabolism (about ~5%); not a clinically significant CYP450 substrate.

Product Information

Available Dosage Forms

For this SFDA-registered product: film‑coated tablet (oral). Other fexofenadine dosage forms may exist in some markets (e.g., oral suspension), but they are not this specific product.

Composition per Dose

Each tablet: 120mg fexofenadine hydrochloride

Generic Availability

Yes

OTC Alternatives

Other OTC second‑generation antihistamines include cetirizine, loratadine, desloratadine, and levocetirizine (availability may vary by country).

Symptom Target

Allergy, Runny Nose

Sedating

No

Reviewed by Al Mujtama Pharmacy Medical Review Team. Last reviewed 22-07-2026