APISAL EYE/NOSE DROPS 15ML

Indications

Approved Uses

Symptomatic cleansing/irrigation and moisturization of the eye and nasal mucosa (e.g., relief of dryness/irritation and helping loosen/remove nasal secretions).

Off-Label Uses

No well-established off-label uses; may be used for general ocular/nasal irrigation (e.g., rinsing away allergens/irritants) consistent with its irrigant function-avoid using as contact lens rinse unless the product is specifically labeled for that purpose.

Dosage & Administration

Dosing by Condition

Ophthalmic dryness/irrigation: 1-2 drops in affected eye(s) as needed (commonly up to several times daily). Nasal dryness/secretions: 1-2 drops in each nostril as needed (may be repeated several times daily).

Initial Dose

Nasal: 2-3 drops per nostril; Ocular: 1-2 drops per eye

Maintenance Dose

2-3 drops per nostril or 1-2 drops per eye, 3-6 times daily as needed

Maximum Dose

No established maximum dose; use as needed according to symptoms (follow label directions).

Children's Dosage

Safe for use in infants and children; same dosing as adults (2-3 drops per nostril or 1-2 drops per eye as needed). For neonates and infants, 1-2 drops per nostril is sufficient

Dose Adjustment Notes

No dose adjustment required (including pediatrics, geriatrics, pregnancy/lactation, renal/hepatic impairment).

How to Take

Ophthalmic: Wash hands; avoid touching the dropper tip; tilt head back, pull down lower eyelid, instill 1-2 drops into the conjunctival sac; close eye gently for ~1 minute (do not rub). Nasal: Wash hands; avoid touching the tip; tilt head back (or lie down), instill 1-2 drops into each nostril; allow to drain/blow gently. Replace cap after use.

Side Effects

Common Side Effects

Transient mild stinging/burning or irritation (eye or nose) and temporary blurred vision after ocular instillation.

Side Effect Frequency

Not well quantified; may include transient mild stinging/burning or irritation (eye or nose) and temporary blurred vision after ocular instillation (generally mild and short-lived).

Safety & Warnings

Contraindications

Hypersensitivity to sodium chloride or to any excipient/component of the formulation.

Warnings & Precautions

For external ocular/nasal use only; avoid contaminating the dropper tip and do not share; do not use if solution is discolored/contains particles; discontinue and consult a clinician if pain, vision changes, or persistent/worsening irritation occurs.

Age Restriction

No specific age restriction; can be used in all ages (including infants/neonates) with appropriate administration and hygiene.

Drug Interactions

Drug Interactions

No known clinically significant drug interactions.

Interaction Severity

No clinically significant drug interactions expected.

Food Interaction

No known food interactions / not applicable.

Special Populations

Children

Safe for use in infants and children; same dosing as adults (2-3 drops per nostril or 1-2 drops per eye as needed). For neonates and infants, 1-2 drops per nostril is sufficient

Kidney Impairment

No adjustment needed

Storage & Patient Advice

Missed Dose

Not applicable (used as needed); if using on a schedule, instill when remembered unless it is almost time for the next dose-do not double.

Stopping the Medicine

Safe to stop anytime

Overdose

Overdose is unlikely with ocular/nasal use; if accidentally ingested, clinically significant toxicity is unlikely-manage supportively and seek medical advice if large volumes are ingested or symptoms occur.

Patient Counseling

Sterile 0.9% sodium chloride (saline) drops for eye and nose to rinse/cleanse and moisturize (e.g., dryness/irritation; nasal dryness/congestion due to thick secretions). Wash hands before use; avoid touching the dropper tip to the eye/nose/skin or any surface; for eyes instill into the lower-lid pocket; for nose instill into the nostril with head slightly tilted back. Do not use if solution is cloudy/discolored or if the seal is broken. Store below 25°C. Discard about 28-30 days after opening (or earlier if contamination is suspected).

Monitoring Requirements

No routine monitoring

Pharmacology

Mechanism of Action

Isotonic (0.9%) saline acts as a physiological irrigant that hydrates and mechanically cleanses ocular/nasal surfaces, helping loosen and remove mucus, debris, and irritants without pharmacologic receptor activity.

Onset of Action

Immediate.

Duration of Effect

Short-acting; relief is immediate but typically brief and may require repeat dosing as needed.

Half-Life

Not applicable (no meaningful systemic half-life with topical eye/nose use; negligible systemic absorption).

Bioavailability

Negligible systemic absorption from topical ophthalmic or nasal application

Metabolism

Not applicable; sodium chloride is not metabolized (endogenous ions).

Excretion

Not clinically applicable for topical eye/nose use; any minimal absorbed sodium/chloride would be handled by normal electrolyte homeostasis with renal excretion.

Protein Binding

Not applicable (no protein binding relevance for inorganic ions at topical use with negligible systemic absorption).

Product Information

Available Dosage Forms

Ear/eye/nose drops, solution (dropper container).

Composition per Dose

Each 1 ml: 9 mg sodium chloride (0.9% w/v) in sterile purified water

Generic Availability

Yes

OTC Alternatives

Any sterile isotonic 0.9% sodium chloride eye/nose saline drops (generic or other brands).

Symptom Target

Congestion, Runny Nose, Allergy

Sedating

No

Reviewed by Al Mujtama Pharmacy Medical Review Team. Last reviewed 04-08-2026