Frequently bought together

Brand : ASTATIN

ASTATIN 20/MG FC TAB 30/FC TAB

43.45

Sku : I-000345
Key features
ASTATIN 20 mg film‑coated tablets contain atorvastatin calcium 20 mg as the active ingredient. It selectively and competitively inhibits HMG‑CoA reductase, reducing hepatic cholesterol synthesis and upregulating LDL receptors to increase clearance of LDL‑cholesterol from plasma. ASTATIN is indicated for lowering elevated LDL‑cholesterol in primary hypercholesterolemia and mixed dyslipidemia and for reducing cardiovascular risk associated with hyperlipidemia. Available as a prescription-only film‑coated tablet in packs of 30 tablets.
- Brand: ASTATIN
- Active Ingredient: ATORVASTATIN CALCIUM 20mg
- Strength: 20mg
- Dosage Form: Film-coated tablet
- Pack Size: 30 Tablets
- Route: Oral use
- Prescription Status: Prescription
- Therapeutic Class: Lipid Modifying
- Pharmacological Group: Statins
- Manufacturer: Jamjoom Pharmaceuticals Factory Company
- Country of Origin: Saudi Arabia
- SFDA Registration No.: 0912211440
- Shelf Life: 24 months
- Storage: do not store above 30°c
- Lipid Target: Both: Triglycerides & LDL

Frequently bought together

Description

Specification

Dosage & Administration

Initial Dose

10-20mg once daily. [5, 11, 24]

Dose Adjustment Notes

Assess lipids about 2-4 weeks after initiation or dose change and titrate as needed; when used with interacting drugs, use the lowest effective dose and follow label-based limits (e.g., avoid/limit with strong CYP3A4 inhibitors and cyclosporine due to myopathy risk).

Safety & Warnings

Age Restriction

Adults: indicated for hypercholesterolemia/mixed dyslipidemia and cardiovascular risk reduction. Pediatric use: approved for heterozygous familial hypercholesterolemia (HeFH) in ages 10-17 years; safety/efficacy not established for <10 years. Other pediatric indications (including routine primary prevention) are not established for <18 years.

Drug Interactions

Food Interaction

May be taken with or without food; avoid excessive grapefruit juice (large quantities) because it can increase atorvastatin exposure and myopathy risk.

Pharmacology

Mechanism of Action

Selective, competitive inhibition of HMG‑CoA reductase, reducing hepatic cholesterol synthesis, upregulating LDL receptors, and increasing clearance of LDL‑cholesterol from plasma.