Frequently bought together

Brand : HYOPAN

HYOPAN SYRUP 100ML

Sku : I-002939
Key features
HYOPAN Syrup 100 ml is a syrup containing hyoscine butylbromide 1 mg/ml. It is a peripheral antimuscarinic antispasmodic that competitively blocks muscarinic receptors on peripheral smooth muscle, reducing spasms and cramping with limited central nervous system penetration due to its quaternary ammonium structure. It is used for symptomatic relief of smooth-muscle spasm in the gastrointestinal tract (including IBS-related cramping), biliary tract and genitourinary tract, such as biliary colic and renal/ureteric colic. Available OTC in a 100 ml syrup.
- Brand: HYOPAN
- Active Ingredient: HYOSCINE BUTYLBROMIDE 1mg/ml
- Strength: 1mg/ml
- Dosage Form: Syrup
- Pack Size: 100 ml
- Route: Oral use
- Prescription Status: OTC
- Therapeutic Class: Alimentary Tract & Metabolism
- Drug Class: Peripheral antimuscarinic anticholinergic antispasmodic (quaternary ammonium compound).
- Manufacturer: KUWAIT SAUDI PHARMACEUTICAL INDUSTRIES
- Country of Origin: Kuwait
- SFDA Registration No.: 1505245303
- Shelf Life: 36 months
- Storage: store below 30°c
- Gi Condition: IBS

Frequently bought together

Description

Indications

Approved Uses

Symptomatic relief of smooth-muscle spasm of the gastrointestinal tract (including IBS-related cramping), biliary tract, and genitourinary tract (e.g., biliary colic, renal/ureteric colic).

Dosage & Administration

Dosing by Condition

Adults and adolescents ≥12 years (oral syrup 1 mg/mL): 10-20 mg (10-20 mL) up to 3-4 times daily for GI spasm/IBS; for acute colicky pain, doses in the same range may be used up to 4 times daily as needed. Children 6-12 years: 5-10 mg (5-10 mL) up to 3 times daily (per local labeling where approved).

Initial Dose

10 mg three times daily for Irritable Bowel Syndrome.

Maintenance Dose

10-20 mg (10-20 ml) three to four times daily

Maximum Dose

80 mg per day (adults)

Pharmacology

Mechanism of Action

Competitive antagonism at muscarinic receptors in peripheral smooth muscle (GI, biliary, and genitourinary tracts), reducing spasms and cramping; limited CNS penetration due to quaternary structure.

Half-Life

Approximately 5 hours.

Bioavailability

Very low oral bioavailability, approximately ~1% (single-digit and typically cited around 1%).

Metabolism

Metabolized mainly by hydrolytic cleavage (ester hydrolysis), with limited systemic exposure; metabolites are largely inactive.

Product Information

Available Dosage Forms

Syrup, tablet, solution for injection

Composition per Dose

Each 5 ml: 5 mg hyoscine butylbromide (1 mg/ml)

Generic Availability

Yes

Gi Condition

IBS

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