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TAKEPRON 30/MG HARD CAP 14/CAP
- Sku : I-006230
Key features
Takepron 30mg Caps Capsule, hard 14 Capsules is a prescription hard capsule formulation of the brand TAKEPRON containing the active ingredient lansoprazole 30 mg. It irreversibly inhibits the H+/K+-ATPase (proton pump) in gastric parietal cells, blocking the final step of acid secretion and reducing gastric acid production. It is indicated for duodenal and gastric ulcers, gastroesophageal reflux disease (GERD) and erosive esophagitis, Helicobacter pylori eradication as part of combination therapy, NSAID-associated ulcer treatment and prevention, and Zollinger-Ellison syndrome. Available as hard capsules in a pack of 14 capsules for prescription use.- Brand: TAKEPRON
- Active Ingredient: LANSOPRAZOLE 30mg
- Strength: 30mg
- Dosage Form: Capsule, hard
- Pack Size: 14 Capsules
- Route: Oral use
- Prescription Status: Prescription
- Therapeutic Class: Gastrointestinal
- Pharmacological Group: Proton Pump Inhibitors
- Drug Class: Proton Pump Inhibitor (PPI)
- Manufacturer: APM
- Country of Origin: Jordan
- SFDA Registration No.: 86-119-97
- Shelf Life: 48 months
- Storage: store below 30°c
- Gi Condition: Acid Reflux/GERD, Ulcer
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Indications
Approved Uses
Duodenal ulcer, gastric ulcer, GERD (gastroesophageal reflux disease), erosive esophagitis, Helicobacter pylori eradication (in combination therapy), NSAID-associated ulcer treatment and prevention, Zollinger-Ellison syndrome
Dosage & Administration
Dosing by Condition
Duodenal ulcer: 15-30mg once daily for 4 weeks. Gastric ulcer: 30mg once daily for 8 weeks. GERD/Erosive esophagitis: 30mg once daily for 4-8 weeks. H. pylori eradication: 30mg twice daily for 7-14 days (with antibiotics). Zollinger-Ellison syndrome: 60mg once daily, titrate as needed. NSAID-associated ulcer prevention: 15mg once daily
Initial Dose
30mg once daily in the morning before eating
Maintenance Dose
15-30mg once daily
Maximum Dose
120mg/day (Zollinger-Ellison syndrome); 30mg/day for standard indications
Dose Adjustment Notes
Severe hepatic impairment: do not exceed 30mg/day. Renal impairment: no dose adjustment required. Doses above 30mg/day for Zollinger-Ellison may be divided twice daily
Safety & Warnings
Age Restriction
Not approved under 1 year of age
Drug Interactions
Drug Interactions
Clopidogrel (reduced antiplatelet effect via CYP2C19 inhibition), methotrexate (increased methotrexate toxicity), atazanavir/nelfinavir (reduced antiviral absorption), rilpivirine (reduced efficacy), warfarin (increased INR), digoxin (increased digoxin levels), ketoconazole/itraconazole (reduced antifungal absorption), sucralfate (delayed lansoprazole absorption)
Food Interaction
Take 30-60 minutes before meals (preferably breakfast) for optimal efficacy
Pharmacology
Mechanism of Action
Irreversibly inhibits the H+/K+-ATPase enzyme (proton pump) in gastric parietal cells, blocking the final step of acid secretion and reducing gastric acid production
Duration of Effect
Over 24 hours
Half-Life
1-2 hours
Metabolism
Extensive hepatic metabolism via CYP2C19 (primary) and CYP3A4
Product Information
Composition per Dose
Each hard capsule: 30mg lansoprazole (as enteric-coated granules)
Generic Availability
Yes
Gi Condition
Acid Reflux/GERD, Ulcer
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