ENTEROGERMINA HARD CAP 12/CAP

Benefits & Uses

Primary Benefit

Restores and maintains intestinal microbial balance to support gut health and aid recovery from diarrhea and dysbiosis

Health Claims

Restores intestinal microbial flora disrupted by antibiotic therapy or gastrointestinal infections; supports recovery from acute diarrhea; maintains gut microbial balance

Common Deficiency Symptoms

Not applicable - this is a probiotic supplement, not a nutrient with a deficiency state; indications include diarrhea, intestinal dysbiosis, and disrupted gut flora

Target Population

Adults and children experiencing diarrhea, antibiotic-associated gut dysbiosis, or intestinal flora imbalance; patients undergoing antibiotic therapy

Scientific Evidence Level

Moderate

Onset Timeline

Symptomatic improvement in diarrhea typically observed within 2-5 days of use; gut flora restoration may take 1-2 weeks

Usage & Dosage

Suggested Use

Take 1 capsule 2-3 times daily, orally, with or without food

Serving Size

1 capsule

Servings Per Container

12

Best Time to Take

Any time

Recommended Daily Intake

Adults and children over 12: 2-3 capsules per day; children under 12: as directed by physician

Upper Tolerable Limit

No established upper tolerable limit; clinical studies have used up to 6 billion organisms per day safely

Absorption Enhancers

No specific absorption enhancers required; spore form is inherently resistant to gastric acid ensuring intestinal delivery

Absorption Inhibitors

While the Bacillus clausii strains in this product are resistant to many antibiotics, it is often recommended to administer the probiotic in the interval between antibiotic doses.

Side Effects

Possible Side Effects

Generally well-tolerated at recommended doses; rare reports of mild gastrointestinal discomfort such as bloating or flatulence

Toxicity Risk

Negligible

Upper Tolerable Limit

No established upper tolerable limit; clinical studies have used up to 6 billion organisms per day safely

Safety & Warnings

Contraindications

Contraindication: hypersensitivity to Bacillus clausii (spores) or any excipients. Caution (not a contraindication): use only under medical supervision in severely immunocompromised or critically ill patients due to rare risk of bacteremia/fungemia-like probiotic sepsis.

Children Suitability

Suitable for children who can swallow capsules, typically ages 5 and over; 1-2 capsules per day are recommended. An oral suspension is available for younger children.

Interactions

Medication Interactions

Can be taken during antibiotic therapy due to the polyantibiotic-resistant nature of the strains. Caution is advised with immunosuppressive drugs.

Special Populations

Target Population

Adults and children experiencing diarrhea, antibiotic-associated gut dysbiosis, or intestinal flora imbalance; patients undergoing antibiotic therapy

Children Suitability

Suitable for children who can swallow capsules, typically ages 5 and over; 1-2 capsules per day are recommended. An oral suspension is available for younger children.

Storage & Patient Advice

SFDA Storage Conditions

store below 25°c

Patient Counseling

May be taken with or without food. Swallow capsule whole with water; if unable to swallow, the capsule may be opened and the contents mixed with a small amount of cool/room‑temperature liquid (do not mix with hot liquids). Can be used during/after antibiotic therapy; because Bacillus clausii spores are polyantibiotic‑resistant, strict separation from antibiotic doses is not essential, though spacing by ~2 hours is a reasonable precaution. Seek medical advice before use in immunocompromised patients; stop and consult a clinician if symptoms persist/worsen.

Science & Evidence

Bioavailability Form

Spores. The spore form is highly resistant to stomach acid and bile, ensuring the bacteria reach the intestine intact and alive to colonize the gut.

Scientific Evidence Level

Moderate

Onset Timeline

Symptomatic improvement in diarrhea typically observed within 2-5 days of use; gut flora restoration may take 1-2 weeks

Food Sources

Bacillus clausii is not naturally present in significant quantities in common food sources; it is a soil-origin spore-forming bacterium

Product Information

Supplement Type

Probiotic

Strain Names

Bacillus clausii (polyantibiotic-resistant strains: O/C, N/R, SIN, T)

Cfu Count

2 billion spores (2 × 10⁹ organisms) per capsule

Requires Refrigeration

Shelf-stable