LIVOSTIN NASAL SP 10ML

Indications

Approved Uses

Symptomatic treatment of allergic rhinitis (including seasonal and perennial) such as sneezing, rhinorrhea, and nasal pruritus.

Dosage & Administration

Dosing by Condition

Allergic rhinitis: 2 sprays in each nostril twice daily; if needed may increase to 2 sprays per nostril 3-4 times daily (maximum 4 times daily).

Initial Dose

2 sprays (100 mcl each) into each nostril twice daily

Maintenance Dose

2 sprays into each nostril twice to four times daily

Maximum Dose

2 sprays (0.5 mg/mL) into each nostril twice daily; not to exceed this without medical direction. Treatment should not continue beyond 3 days without improvement, and continuous use should not exceed 10 weeks

Children's Dosage

Approved for children ≥12 years: 2 sprays (0.5 mg/mL) into each nostril twice daily. No established dosing for children 6-11 years; use in this age group is not supported by available clinical data

How to Take

Shake well before each use; gently blow/clear the nose; keep head upright or slightly forward; insert nozzle into one nostril while closing the other and spray while breathing in gently through the nose; repeat for the other nostril as directed; avoid contact with eyes; wipe/clean the nozzle and replace the cap after use.

How to Prepare

Shake well before each use; prime the pump before first use (and if not used for several days) until a fine mist appears

Side Effects

Common Side Effects

Local nasal effects (irritation/burning/stinging, sneezing), headache; less commonly somnolence/fatigue; cough can occur.

Side Effect Frequency

Common: local nasal irritation/burning/stinging, sneezing, headache; somnolence/fatigue can occur. Uncommon/rare: epistaxis and hypersensitivity reactions; anaphylaxis is very rare.

Safety & Warnings

Contraindications

Hypersensitivity to levocabastine or any excipients.

Warnings & Precautions

Shake well before use; avoid eye contact; may cause mild drowsiness-use caution with driving/alcohol/CNS depressants; use with caution in renal impairment; discontinue and seek care if hypersensitivity occurs; use in children per labeled age (typically ≥12 years).

Age Restriction

Approved for adults and children ≥12 years (not recommended/insufficient data <12 years).

Driving Warning

May Cause Drowsiness

Drug Interactions

Food Interaction

No restriction

Alcohol Interaction

Avoid

Special Populations

Pregnancy

FDA Pregnancy Category C

Breastfeeding

Use with caution; limited absorption expected to cause no adverse effects in breastfed infants.

Children

Approved for children ≥12 years: 2 sprays (0.5 mg/mL) into each nostril twice daily. No established dosing for children 6-11 years; use in this age group is not supported by available clinical data

Storage & Patient Advice

Preparation Instructions

Shake well before each use; prime the pump before first use (and if not used for several days) until a fine mist appears

Stopping the Medicine

Safe to stop anytime; no tapering required (seek medical advice if symptoms persist or worsen).

Patient Counseling

Shake well before each use; clear the nose first; use correct spray technique and avoid spraying into eyes; do not exceed 2 sprays per nostril up to 4 times daily; possible mild drowsiness-use caution with driving/alcohol/CNS depressants; clean the nozzle and do not share the spray; seek medical advice if symptoms persist/worsen (commonly if no improvement within a few days); store below 25°C.

Monitoring Requirements

No routine monitoring

Pharmacology

Mechanism of Action

Selective competitive H1-receptor antagonist that blocks histamine effects in the nasal mucosa, reducing allergic symptoms (sneezing, itching, rhinorrhea).

Onset of Action

Typically within about 10-15 minutes after intranasal use.

Duration of Effect

Approximately up to 12 hours per dose (supporting twice-daily dosing in many patients).

Product Information

Available Dosage Forms

Nasal spray, suspension (this product); levocabastine is also available in some markets as ophthalmic suspension (eye drops).

Composition per Dose

Each 100 mcl spray: 50 mcg levocabastine as hydrochloride (0.5 mg/ml suspension)

OTC Alternatives

Intranasal corticosteroids (e.g., fluticasone, budesonide) and oral second-generation antihistamines (e.g., cetirizine, loratadine) are common OTC alternatives for allergic rhinitis; availability of azelastine as OTC varies by country.

Symptom Target

Allergy, Runny Nose

Sedating

Yes

Reviewed by Al Mujtama Pharmacy Medical Review Team. Last reviewed 10-08-2026