GAVISCON DOUBLE ACTION CHEW TAB 32/TAB

Indications

Approved Uses

Symptomatic relief of gastro‑oesophageal reflux (acid regurgitation/heartburn) and indigestion/dyspepsia related to reflux, including post‑prandial symptoms; may be used in pregnancy for reflux symptoms.

Dosage & Administration

How to Take

Chew tablets thoroughly before swallowing. Take after meals and at bedtime. Do not swallow whole. Can be taken without water.

Drug Interactions

Food Interaction

Take after meals and at bedtime; post‑prandial dosing improves raft formation and clinical effect.

Special Populations

Liver Impairment

No adjustment needed.

Storage & Patient Advice

Stopping the Medicine

Safe to stop anytime; no tapering required

Pharmacology

Mechanism of Action

Sodium alginate reacts with gastric acid to form a viscous, near‑neutral ‘raft’ that floats on stomach contents and reduces reflux; sodium bicarbonate and calcium carbonate neutralize acid and support raft formation/raise gastric pH.

Onset of Action

Rapid-within minutes (typically ~3-5 minutes).

Duration of Effect

Up to about 4 hours (often ~2-4 hours).

Half-Life

Not applicable / not clinically meaningful (local GI action with minimal systemic absorption).

Bioavailability

Negligible systemic bioavailability; primarily local gastric action (raft formation + antacid effect).

Metabolism

Not systemically metabolized; alginate is not absorbed, and carbonate/bicarbonate are consumed in acid-base neutralization in the stomach.

Excretion

Alginate raft is not absorbed and is eliminated via the GI tract (feces); absorbed sodium/calcium (if any) are handled physiologically and excreted mainly renally.

Protein Binding

Not applicable (no meaningful systemic absorption; protein binding not relevant).

Product Information

Available Dosage Forms

Chewable tablet (this specific SFDA-registered product).

Gi Condition

Acid Reflux/GERD

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