FERPLEX 40/MG ORAL SOL 20/VIALS

Benefits & Uses

• Treats iron deficiency and iron deficiency anemia, whether latent or overt, in both children and adults.
• Used in cases of iron deficiency anemia secondary to chronic blood loss.
• Indicated for the treatment of iron deficiency anemia during pregnancy and breastfeeding.
• Helps restore normal iron stores in the body, with treatment typically continuing for 2 to 3 months until full recovery.

Usage & Dosage

• Adults: 1 to 2 vials per day (equivalent to 40-80 mg of Fe3+), given in 2 administrations, preferably before food.
• Children: 1.5 ml/kg/day from a vial (equivalent to 4 mg/kg/day of Fe3+), given in 2 administrations, preferably before food.
• The solution may be drunk directly from the vial or diluted in natural water.
• Duration of treatment: Treatment should be continued until total recovery of normal iron stores, usually for 2-3 months.
• Maximum daily dose: Adults: up to 1,600 mg/day of iron proteinsuccinylate. Children: up to 1.5 ml/kg/day of iron proteinsuccinylate. No clinical data are available on the efficacy or tolerability of higher dosages.

Safety & Warnings

• The treatment should not exceed 6 months, unless in cases of persisting bleeding, menorrhagia, or pregnancy.
• Any disease possibly underlying iron deficiency or iron deficiency anemia must be ascertained and properly treated.
• As the product contains milk proteins, it must be used with caution in patients suffering from milk-protein intolerance, who may have allergic reactions.
• Ferplex vials contain sorbitol; patients with rare hereditary fructose intolerance must not take this medicine.
• Ferplex vials contain parabens (methyl-p-hydroxybenzoate sodium salt, propyl-p-hydroxybenzoate sodium salt) that may cause delayed allergic reactions.
• No particular warnings are required about risks of tolerance or addiction.

Science & Evidence

• Ferplex 40 mg contains iron proteinsuccinylate, with each vial providing 800 mg of iron proteinsuccinylate equivalent to 40 mg of ferric iron (Fe3+).
• The active ingredient is formulated as a ferric iron (Fe3+) compound delivered in oral liquid vials.
• Clinical trials on the product were conducted at the specified dosage levels: up to 1,600 mg per day of iron proteinsuccinylate in adults, and 1.5 ml/kg/day in children.
• The product is indicated for the treatment of latent or overt iron deficiency and iron deficiency anemia, including cases secondary to chronic blood loss, pregnancy, and breastfeeding.
• Treatment duration in clinical use is typically 2 to 3 months, continued until full recovery of normal iron stores is achieved.
• The product contains milk proteins, which are relevant for patients with milk-protein intolerance, as allergic reactions may occur in such individuals.
• Ferplex vials contain sorbitol, a sugar alcohol, which is a relevant consideration for patients with hereditary fructose intolerance.
• The formulation contains parabens (methyl-p-hydroxybenzoate sodium salt and propyl-p-hydroxybenzoate sodium salt), which are known to potentially cause delayed allergic reactions in some individuals.

Product Information

• Brand: Ferplex
• Pack Size: 20 Vials
• Active Ingredient: Iron Proteinsuccinylate 800 mg (equivalent to 40 mg of Fe3+) per vial
• Category: Iron & Anemia Supplements
• Indicated For: Treatment of iron deficiency and iron deficiency anemia (latent or overt), including cases secondary to chronic blood loss, pregnancy, and breastfeeding, in children and adults
• Adult Dose: 1 to 2 vials per day (equivalent to 40-80 mg of Fe3+), in 2 administrations, preferably before food
• Children's Dose: 1.5 ml/kg/day (equivalent to 4 mg/kg/day of Fe3+), in 2 administrations, preferably before food
• How to Take: Drink the solution directly from the vial or dilute in natural water
• Recommended Treatment Duration: Usually 2 to 3 months, until normal iron stores are fully recovered; treatment should not exceed 6 months unless in cases of persisting bleeding, menorrhagia, or pregnancy
• Contains Sorbitol: Patients with rare hereditary fructose intolerance must not take this medicine
• Contains Milk Proteins: Must be used with caution in patients with milk-protein intolerance due to risk of allergic reactions
• Contains Parabens: Methyl-p-hydroxybenzoate sodium salt and propyl-p-hydroxybenzoate sodium salt, which may cause delayed allergic reactions