CALCINATE 600/MG FC TAB 60/FC TAB

Benefits & Uses

Primary Benefit

Supports bone strength, dental health, and prevention of calcium deficiency

Health Claims

Contributes to normal bone and teeth maintenance; supports muscle function and nerve transmission; helps prevent and treat calcium deficiency; reduces risk of osteoporosis when combined with adequate Vitamin D

Common Deficiency Symptoms

Muscle cramps and spasms, numbness or tingling in extremities, brittle nails, dental problems, osteopenia, osteoporosis, fatigue, and in severe cases tetany

Target Population

Postmenopausal women, elderly adults over 50, individuals with low dietary calcium intake, pregnant and breastfeeding women, adolescents during peak bone mass development, and patients on corticosteroid therapy

Scientific Evidence Level

Strong

Onset Timeline

Serum calcium levels normalize within days to weeks with supplementation; measurable improvements in bone mineral density typically observed after 6-12 months of consistent use

Usage & Dosage

Suggested Use

Take one tablet up to three times daily with food or as directed by your doctor.

Serving Size

1 film-coated tablet

Servings Per Container

60

Best Time to Take

With meals - stomach acid produced during eating enhances calcium carbonate absorption

Recommended Daily Intake

Adults: 1000-1200mg elemental calcium/day; Pregnant/Lactating women: 1000-1300mg/day

Upper Tolerable Limit

2500mg elemental calcium/day for adults aged 19-50; 2000mg/day for adults over 50

Absorption Enhancers

Take with food to stimulate gastric acid; Vitamin D3 significantly enhances intestinal calcium absorption; acidic environment improves solubility

Absorption Inhibitors

High-oxalate foods (spinach, rhubarb), phytates (whole grains, legumes), excess dietary fiber, proton pump inhibitors (PPIs), high-dose iron supplements taken simultaneously, caffeine, and alcohol

Side Effects

Possible Side Effects

Constipation, bloating, and flatulence are most common; high doses may cause hypercalcemia, hypercalciuria, nausea, and kidney stones; milk-alkali syndrome with excessive long-term use

Toxicity Risk

Medium

Upper Tolerable Limit

2500mg elemental calcium/day for adults aged 19-50; 2000mg/day for adults over 50

Safety & Warnings

Contraindications

Hypercalcemia; hypercalciuria; nephrolithiasis (calcium-containing kidney stones) or strong history of stones; severe renal impairment; conditions causing hypercalcemia (e.g., hyperparathyroidism, sarcoidosis)

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Safe (compatible with breastfeeding when used at recommended doses; avoid excessive intake)

Children Suitability

Consult a physician for use in children under 12; adolescents 12-18 may use under medical guidance as calcium requirements are high during growth

Interactions

Medication Interactions

Reduces absorption of tetracycline and fluoroquinolone antibiotics, bisphosphonates, levothyroxine, and iron supplements - take at least 2 hours apart; may reduce effectiveness of calcium channel blockers; antacid effect may alter absorption of other oral medications

Supplement Interactions

Competes with iron and zinc for absorption - take separately; high calcium intake may reduce magnesium absorption; avoid concurrent use with high-dose magnesium antacids

Synergistic Nutrients

Vitamin D3 (enhances intestinal calcium absorption), Vitamin K2/MK-7 (directs calcium to bones and away from arteries), Magnesium (supports bone matrix and calcium metabolism), Phosphorus

Special Populations

Target Population

Postmenopausal women, elderly adults over 50, individuals with low dietary calcium intake, pregnant and breastfeeding women, adolescents during peak bone mass development, and patients on corticosteroid therapy

Children Suitability

Consult a physician for use in children under 12; adolescents 12-18 may use under medical guidance as calcium requirements are high during growth

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Safe (compatible with breastfeeding when used at recommended doses; avoid excessive intake)

Storage & Patient Advice

SFDA Storage Conditions

Store below 30°C , Protect from light and moisture

Patient Counseling

Take CALCINATE (calcium carbonate 600 mg) by mouth with meals/food (calcium carbonate is better absorbed with gastric acid). If more than one tablet/day is needed, split doses (absorption is saturable; ~500 mg elemental calcium per dose is absorbed best). Separate from interacting medicines: levothyroxine and iron by at least 4 hours; tetracyclines/fluoroquinolones and bisphosphonates by at least 2 hours before or 4-6 hours after calcium. Maintain adequate vitamin D intake. Common effects: constipation/bloating-ensure adequate fluids and dietary fiber. Do not exceed the recommended total daily calcium intake from all sources unless advised; seek medical advice if symptoms of hypercalcemia occur (e.g., nausea/vomiting, constipation, polyuria/polydipsia, confusion) or if you have kidney stones/renal impairment.

Science & Evidence

Bioavailability Form

Calcium Carbonate - contains 40% elemental calcium by weight; requires gastric acid for dissolution, best absorbed in divided doses with food

Scientific Evidence Level

Strong

Onset Timeline

Serum calcium levels normalize within days to weeks with supplementation; measurable improvements in bone mineral density typically observed after 6-12 months of consistent use

Food Sources

Dairy products (milk, yogurt, cheese), fortified plant-based milks, canned sardines and salmon (with bones), tofu made with calcium sulfate, and leafy greens like kale and collard greens.

Product Information

Supplement Type

Mineral

Allergen Info

No common allergens declared; free from gluten, soy, and fish-derived ingredients based on active ingredient profile - excipients should be verified on product label

Suitable for Vegetarians

Yes

Calcium Included

Yes - Calcium Carbonate 600mg (providing approximately 240mg elemental calcium per tablet)

Vitamin K Included

No