JP VITAL E 400/MG SG CAP 30/SG CAP

Benefits & Uses

Primary Benefit

Provides antioxidant protection by neutralizing free radicals and supports immune function and skin health.

Health Claims

Contributes to protection of cells from oxidative stress; supports immune system function; contributes to normal skin health; supports cardiovascular health as an antioxidant

Common Deficiency Symptoms

Muscle weakness, difficulty with coordination and walking (ataxia), numbness and tingling, vision deterioration, and a weakened immune response.

Target Population

Adults with Vitamin E deficiency, individuals with fat malabsorption disorders, people with high oxidative stress, those with low dietary fat intake

Usage & Dosage

Suggested Use

Take 1 capsule daily, preferably with a meal containing fat.

Serving Size

1 softgel capsule

Servings Per Container

30

Best Time to Take

With meals

Recommended Daily Intake

Adults: 15 mg/day (22.4 IU); therapeutic doses of 400 mg are used under clinical guidance

Upper Tolerable Limit

1000 mg/day (1500 IU natural alpha-tocopherol) for adults

Absorption Enhancers

Dietary fat significantly enhances absorption; medium-chain triglycerides (MCT oil) may further improve uptake

Absorption Inhibitors

Very low-fat meals reduce absorption; mineral oil, orlistat, and cholestyramine impair Vitamin E absorption; high-dose iron supplements may oxidize Vitamin E

Side Effects

Possible Side Effects

High doses (>1000 mg/day) can increase the risk of bleeding. Other potential side effects include nausea, diarrhea, fatigue, and headache.

Upper Tolerable Limit

1000 mg/day (1500 IU natural alpha-tocopherol) for adults

Safety & Warnings

Contraindications

Hypersensitivity to vitamin E/tocopherols or excipients; avoid/use only with medical supervision in bleeding disorders or with anticoagulant/antiplatelet therapy; discontinue before elective surgery

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Generally compatible at recommended dietary doses; avoid high-dose (400 mg) supplementation during breastfeeding unless medically indicated-consult a clinician

Children Suitability

Not recommended for children without medical supervision; adult formulation at 400 mg exceeds pediatric requirements

Interactions

Medication Interactions

Anticoagulants (warfarin): high-dose Vitamin E enhances anticoagulant effect and increases bleeding risk; statins and niacin: may reduce their efficacy; chemotherapy and radiotherapy: antioxidant effect may interfere with treatment

Supplement Interactions

High-dose Vitamin E may antagonize Vitamin K activity; high-dose iron supplements may reduce Vitamin E efficacy; large doses of Vitamin A may compete for absorption

Synergistic Nutrients

Vitamin C regenerates oxidized Vitamin E; Selenium works synergistically as a co-antioxidant; Vitamin K2 should be monitored when taking high-dose Vitamin E

Special Populations

Target Population

Adults with Vitamin E deficiency, individuals with fat malabsorption disorders, people with high oxidative stress, those with low dietary fat intake

Children Suitability

Not recommended for children without medical supervision; adult formulation at 400 mg exceeds pediatric requirements

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Generally compatible at recommended dietary doses; avoid high-dose (400 mg) supplementation during breastfeeding unless medically indicated-consult a clinician

Storage & Patient Advice

SFDA Storage Conditions

do not store above 30°c

Patient Counseling

Take 1 capsule (400 mg) by mouth as directed; take with a meal (preferably containing fat) to improve absorption. Do not exceed the labeled/recommended dose unless advised by a clinician. Consult a doctor/pharmacist before use if you take anticoagulants/antiplatelets (e.g., warfarin, DOACs, aspirin, clopidogrel), have a bleeding disorder, or are scheduled for surgery/dental procedures; consider stopping high‑dose vitamin E 1-2 weeks before elective surgery if advised. Seek medical advice if unusual bruising/bleeding occurs.

Science & Evidence

Bioavailability Form

Alpha-Tocopherol - the most biologically active natural form of Vitamin E, preferentially retained by the liver and incorporated into lipoproteins for tissue delivery

Water or Fat Soluble

Fat-soluble

Food Sources

Vegetable oils (sunflower, wheat germ), nuts (almonds, peanuts), seeds (sunflower seeds), and green leafy vegetables.

Product Information

Supplement Type

Vitamin

Certification

SFDA registered (134-368-15); manufactured under GMP by Jamjoom Pharmaceuticals Factory Company, Saudi Arabia

Multivitamin Target

Single Nutrient

Nutrient Count

1