THIOTACID 600/MG FC TAB 30/TAB

Benefits & Uses

Primary Benefit

Provides potent antioxidant protection, supports nerve function in diabetic peripheral neuropathy, and improves insulin sensitivity and glucose metabolism.

Health Claims

Clinically supported for reduction of symptoms of diabetic peripheral neuropathy; potent antioxidant activity reducing oxidative stress; improvement of insulin sensitivity and glucose uptake; supports mitochondrial energy metabolism.

Common Deficiency Symptoms

Alpha lipoic acid is synthesized endogenously; deficiency is not a recognized clinical condition, but low levels are associated with increased oxidative stress, peripheral neuropathy symptoms, and impaired glucose metabolism.

Target Population

Adults with diabetic peripheral neuropathy, individuals with type 2 diabetes, patients with metabolic syndrome, adults seeking antioxidant support, individuals with oxidative stress-related conditions.

Scientific Evidence Level

Strong

Usage & Dosage

Suggested Use

Take 1 tablet daily, preferably 30 minutes before a meal on an empty stomach.

Serving Size

1 film-coated tablet

Servings Per Container

30

Best Time to Take

30 minutes before a meal on an empty stomach for optimal absorption; morning for metabolic goals or evening for neuropathy symptom management.

Recommended Daily Intake

Adults: 600mg/day for therapeutic use (diabetic neuropathy); general antioxidant use: 100-300mg/day.

Upper Tolerable Limit

No established official upper tolerable limit; clinical studies have used up to 1800mg/day without serious adverse effects; doses above 600mg/day should be medically supervised.

Absorption Enhancers

Taking on an empty stomach increases peak plasma concentration; R-ALA form has superior bioavailability compared to S-ALA.

Absorption Inhibitors

Food can significantly reduce the absorption and bioavailability of Alpha Lipoic Acid.

Side Effects

Possible Side Effects

Generally well-tolerated at 600mg/day; possible side effects include nausea, vomiting, stomach upset, skin rash (rare), headache, and hypoglycemia in diabetic patients on concurrent antidiabetic therapy.

Toxicity Risk

Low

Upper Tolerable Limit

No established official upper tolerable limit; clinical studies have used up to 1800mg/day without serious adverse effects; doses above 600mg/day should be medically supervised.

Special Populations

Target Population

Adults with diabetic peripheral neuropathy, individuals with type 2 diabetes, patients with metabolic syndrome, adults seeking antioxidant support, individuals with oxidative stress-related conditions.

Storage & Patient Advice

SFDA Storage Conditions

do not store above 25°c

Patient Counseling

Take 1 tablet (600 mg) orally once daily, preferably on an empty stomach about 30 minutes before food to optimize absorption; if gastrointestinal upset occurs, it may be taken with food. If you have diabetes or use insulin/oral glucose‑lowering medicines, monitor blood glucose more closely as alpha‑lipoic acid may lower glucose. If you have thyroid disease or take thyroid hormone (e.g., levothyroxine), consult your clinician and separate administration by at least 2 hours. Avoid heavy alcohol use (risk of thiamine deficiency/neuropathy). Do not exceed the recommended dose without medical advice. Store below 25°C.

Science & Evidence

Bioavailability Form

Alpha Lipoic Acid (racemic R/S-ALA) - the R-form is the biologically active enantiomer; oral bioavailability is approximately 30-40% due to first-pass metabolism

Water or Fat Soluble

Both water- and fat-soluble

Scientific Evidence Level

Strong

Product Information

Supplement Type

Antioxidant

Certification

SFDA registered (Registration No. 609234147); manufactured under GMP by Eva Pharma, Egypt

Plant Source

Not applicable - Alpha Lipoic Acid is a naturally occurring organosulfur compound synthesized endogenously in humans and animals; not derived from a plant source

Standardized Extract

Not applicable - Alpha Lipoic Acid is a defined synthetic/semi-synthetic compound (600mg per tablet), not a standardized botanical extract