THIOTACID 300/MG FC TAB 60/TAB

Benefits & Uses

Primary Benefit

Acts as a powerful antioxidant, supporting nerve health and glucose metabolism.

Health Claims

Supports antioxidant protection against free radicals. Helps maintain healthy nerve function, particularly in diabetic neuropathy. Aids in the metabolism of carbohydrates to produce energy.

Common Deficiency Symptoms

ALA is endogenously synthesized; deficiency is not a recognized clinical condition, but low levels are associated with increased oxidative stress, peripheral neuropathy symptoms, and impaired glucose metabolism

Target Population

Adults with diabetic peripheral neuropathy, individuals with high oxidative stress, patients with metabolic syndrome or insulin resistance, and adults seeking antioxidant support

Scientific Evidence Level

Moderate

Onset Timeline

Blood levels peak within 30-60 minutes of oral intake, but noticeable clinical benefits for nerve function may take several weeks to months of consistent use.

Usage & Dosage

Suggested Use

Take 1 tablet daily, preferably on an empty stomach or as directed by a physician

Serving Size

1 film-coated tablet

Servings Per Container

60

Best Time to Take

30-60 minutes before a meal for optimal absorption

Recommended Daily Intake

Adults: 300-600 mg/day for therapeutic use; no established RDA as the body synthesizes small amounts endogenously

Upper Tolerable Limit

No established official UL; doses up to 1800 mg/day have been used in clinical trials without serious adverse effects

Side Effects

Possible Side Effects

Generally well-tolerated at 300 mg/day; higher doses may cause nausea, vomiting, headache, skin rash, or hypoglycemia in diabetic patients; rare reports of insomnia at high doses

Toxicity Risk

Low

Upper Tolerable Limit

No established official UL; doses up to 1800 mg/day have been used in clinical trials without serious adverse effects

Safety & Warnings

Contraindications

Contraindication: known hypersensitivity to alpha lipoic acid (or any excipients). Cautions/precautions (not contraindications): diabetes or concomitant insulin/oral hypoglycemics (risk of hypoglycemia), thiamine (vitamin B1) deficiency/alcohol misuse (risk of precipitating deficiency-consider thiamine), and thyroid disorders/thyroid hormone therapy (possible interference with thyroid hormone levels).

Interactions

Synergistic Nutrients

Vitamin C, Vitamin E, Coenzyme Q10, and Glutathione - ALA regenerates these antioxidants; B vitamins support mitochondrial energy metabolism alongside ALA

Special Populations

Target Population

Adults with diabetic peripheral neuropathy, individuals with high oxidative stress, patients with metabolic syndrome or insulin resistance, and adults seeking antioxidant support

Storage & Patient Advice

SFDA Storage Conditions

store below 30°c

Patient Counseling

Take on an empty stomach (about 30 minutes before meals) for best absorption; if GI upset occurs, it may be taken with food but absorption may be reduced. If you have diabetes or use glucose‑lowering medicines, monitor blood glucose closely as alpha‑lipoic acid may improve insulin sensitivity and lower glucose. Separate from mineral supplements (e.g., iron, magnesium, zinc, calcium) by at least 2 hours due to chelation/reduced absorption. Use caution/seek medical advice if you have thyroid disease or are taking thyroid hormone (ALA may affect thyroid hormone levels) and if you drink large amounts of alcohol or have thiamine deficiency risk. Do not exceed the labeled dose without medical advice. Store below 30°C.

Science & Evidence

Bioavailability Form

Alpha Lipoic Acid (racemic R/S-ALA) - the R-form is the naturally occurring, more bioavailable enantiomer; oral bioavailability is approximately 30-40% due to first-pass metabolism

Water or Fat Soluble

Water-or-fat-soluble

Scientific Evidence Level

Moderate

Onset Timeline

Blood levels peak within 30-60 minutes of oral intake, but noticeable clinical benefits for nerve function may take several weeks to months of consistent use.

Product Information

Supplement Type

Organosulfur compound

Multivitamin Target

Single Nutrient

Nutrient Count

1