OTRIVIN CHILD 0.05% NASAL DROPS ORIGINAL 10ML

Indications

Approved Uses

Temporary relief of nasal congestion due to common cold and rhinitis (including allergic rhinitis/hay fever); may also be used for congestion associated with sinusitis as symptomatic relief.

Dosage & Administration

Initial Dose

1-2 drops of 0.05% solution in each nostril.

Maintenance Dose

1-2 drops of 0.05% solution in each nostril every 8-10 hours.

Maximum Dose

Maximum: 3 doses (applications) in 24 hours; limit duration to no more than 5-7 consecutive days.

Children's Dosage

Children 2-11 years: 1-2 drops of 0.05% solution into each nostril, 1-2 times daily. Do not use for more than 5 days. Not recommended for children under 2 years of age.

Dose Adjustment Notes

Use the lowest effective dose for the shortest duration; do not use for more than 5 consecutive days (unless directed by a clinician) to reduce risk of rebound congestion.

How to Take

For nasal use (topical intranasal): Gently blow the nose; keep the head slightly tilted back (or lie down) and instill 1-2 drops into each nostril using the dropper; avoid touching the dropper tip to the nose; keep the head back briefly to allow distribution; wipe/clean the tip and recap; do not share the bottle.

Side Effects

Common Side Effects

Nasal dryness, burning/stinging/irritation, sneezing, and increased nasal discharge; rebound congestion (rhinitis medicamentosa) can occur with prolonged or excessive use.

Side Effect Frequency

Common: local nasal irritation/burning/stinging, dryness, sneezing. Uncommon: headache, nausea, palpitations. Important risk with prolonged/excessive use: rebound congestion (rhinitis medicamentosa). Rare: hypertension, tachycardia, CNS effects (e.g., insomnia/restlessness), especially with overuse or in young children.

Safety & Warnings

Warnings & Precautions

Do not use longer than 5-7 days and do not exceed recommended dose/frequency; use with caution in hypertension, cardiovascular disease, hyperthyroidism, diabetes, pheochromocytoma, and prostatic hypertrophy; avoid concomitant sympathomimetics; avoid eye contact; keep out of reach of children and seek urgent help if ingested; not recommended for children <2 years.

Drug Interactions

Drug Interactions

Clinically relevant interactions: MAO inhibitors (and within 14 days) - risk of hypertensive crisis; tricyclic antidepressants - may potentiate pressor/cardiac effects; other sympathomimetics (including other decongestants/stimulants) - additive cardiovascular/CNS effects; caution with antihypertensives due to possible blunting of BP control (clinical significance variable).

Interaction Severity

MAJOR: Concomitant or recent (within 14 days) MAO inhibitors-risk of significant hypertension/pressor response. MODERATE: Tricyclic/tetracyclic antidepressants and other sympathomimetics-additive pressor/cardiac effects. MODERATE/monitor: Antihypertensives-possible attenuation of BP control in susceptible patients.

Food Interaction

No clinically relevant food interactions.

Special Populations

Children

Children 2-11 years: 1-2 drops of 0.05% solution into each nostril, 1-2 times daily. Do not use for more than 5 days. Not recommended for children under 2 years of age.

Kidney Impairment

No adjustment needed

Storage & Patient Advice

Stopping the Medicine

Stop when no longer needed and do not use longer than 5-7 days; if rebound congestion (rhinitis medicamentosa) occurs after prolonged use, discontinue and manage supportively (some clinicians taper or switch to intranasal corticosteroid/saline to ease withdrawal).

Overdose

Overdose/accidental ingestion (especially in children) may cause CNS depression (drowsiness, coma), respiratory depression, hypothermia, bradycardia, hypotension or hypertension, and occasionally agitation/tachycardia; management is urgent medical assessment with supportive care and cardiorespiratory monitoring (consider decontamination per toxicology guidance if significant ingestion and early presentation).

Monitoring Requirements

No routine monitoring

Pharmacology

Mechanism of Action

Topical alpha-adrenergic agonist causing vasoconstriction of nasal mucosal blood vessels, reducing edema and nasal congestion.

Bioavailability

Minimal systemic absorption when used intranasally at recommended doses; primarily local effect.

Product Information

Composition per Dose

Each 1 ml (approximately 30 drops): 0.5 mg xylometazoline hydrochloride (0.05%)

Generic Availability

Yes

OTC Alternatives

Non-medicated: saline drops/spray. Other topical decongestants: oxymetazoline nasal spray/drops (age-appropriate). If allergic symptoms predominate: intranasal corticosteroid sprays (e.g., fluticasone/mometasone) or oral/non-sedating antihistamines (age-appropriate).

Symptom Target

Congestion

Sedating

No

Reviewed by Al Mujtama Pharmacy Medical Review Team. Last reviewed 03-06-2026