ENTEROGERMINA ORAL SUSP 5ML×20/BOTTLE

Benefits & Uses

Primary Benefit

Restores and maintains intestinal microbial balance, supporting gut health and recovery from antibiotic-associated dysbiosis

Health Claims

Restores intestinal flora altered by antibiotic therapy, gastrointestinal infections, or dietary imbalances; supports recovery of gut microbiota balance

Common Deficiency Symptoms

Gut dysbiosis symptoms: diarrhea, bloating, abdominal discomfort, altered bowel habits following antibiotic therapy or gastrointestinal infections

Target Population

Adults and children experiencing antibiotic-associated diarrhea, acute gastroenteritis, or gut dysbiosis; individuals requiring microbiota restoration

Scientific Evidence Level

Moderate

Usage & Dosage

Suggested Use

Shake the vial, twist off the top, and consume the contents directly or diluted in water or other beverages like milk, tea, or orange juice. Take at regular intervals.

Serving Size

1 vial (5 mL)

Servings Per Container

20

Best Time to Take

Between meals or at least 2 hours apart from antibiotic doses

Recommended Daily Intake

Adults and children over 12: 2-3 vials per day; Children 2-12: 1-2 vials per day; Infants: 1 vial per day

Upper Tolerable Limit

Unknown, but excessive doses generally do not cause side effects.

Absorption Enhancers

Administration between meals improves spore survival and intestinal colonization

Absorption Inhibitors

To ensure effectiveness, it should be taken between antibiotic doses, with a suggested gap of at least 2-3 hours.

Side Effects

Possible Side Effects

Generally well-tolerated. Rare side effects may include skin rash, urticaria, and angioedema. In immunocompromised patients, there have been reports of bacteremia or sepsis.

Toxicity Risk

Negligible

Upper Tolerable Limit

Unknown, but excessive doses generally do not cause side effects.

Safety & Warnings

Contraindications

Known hypersensitivity to Bacillus clausii (or any excipients); use with caution/medical supervision in immunocompromised or severely ill (especially hospitalized/central line) patients due to rare risk of probiotic-associated bacteremia.

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Consult Doctor

Children Suitability

Suitable for infants and children of all ages under medical supervision; dosage adjusted by age

Interactions

Medication Interactions

Can be taken during antibiotic therapy but should be administered between doses to maintain effectiveness. Use with caution in patients on immunosuppressants.

Synergistic Nutrients

Can be taken alongside Oral Rehydration Solution (ORS) and zinc to manage diarrhea.

Special Populations

Target Population

Adults and children experiencing antibiotic-associated diarrhea, acute gastroenteritis, or gut dysbiosis; individuals requiring microbiota restoration

Children Suitability

Suitable for infants and children of all ages under medical supervision; dosage adjusted by age

Pregnancy Safety

Consult Doctor

Breastfeeding Safety

Consult Doctor

Storage & Patient Advice

SFDA Storage Conditions

store below 30°c

Patient Counseling

Shake well before use; take orally only and use immediately after opening. If taking antibiotics, separate administration by at least 2 hours (take between antibiotic doses). Seek medical advice if symptoms persist/worsen after a few days, and immunocompromised patients should consult a physician before use.

Science & Evidence

Bioavailability Form

Spores of Bacillus clausii, which are highly resistant to stomach acid and bile, allowing them to reach the intestine intact where they germinate into active bacteria.

Scientific Evidence Level

Moderate

Food Sources

Bacillus clausii is not naturally present in significant quantities in common food sources; it is a pharmaceutical-grade probiotic strain

Product Information

Supplement Type

Probiotic

Certification

SFDA registered (Registration No. 7-1359-2018); manufactured by Sanofi-Aventis S.p.A., Italy under GMP standards

Strain Names

Bacillus clausii O/C, Bacillus clausii N/R, Bacillus clausii SIN, Bacillus clausii T.

Cfu Count

6 billion spores per vial

Requires Refrigeration

Shelf-stable