ESSENTIAL D-3 1000 IU 100 TAB

Benefits & Uses

Primary Benefit

Supports bone health, immune function, and calcium absorption.

Health Claims

Contributes to normal bone and teeth maintenance; supports calcium and phosphorus absorption; supports normal immune function; helps maintain normal muscle function

Common Deficiency Symptoms

Fatigue, bone pain, muscle weakness, frequent infections, depression, impaired wound healing, hair loss

Target Population

Adults with limited sun exposure, elderly individuals (>65 years), dark-skinned individuals, people with malabsorption disorders, pregnant and breastfeeding women, individuals with osteoporosis risk

Scientific Evidence Level

Strong

Onset Timeline

Blood levels typically improve in 8-12 weeks, with bone health benefits observed after 3-6 months of consistent use.

Usage & Dosage

Suggested Use

Take 1 capsule daily with a meal containing fat.

Serving Size

1 Capsule

Servings Per Container

100

Best Time to Take

With meals (preferably the largest fat-containing meal of the day)

Recommended Daily Intake

Adults: 600-800 IU/day (15-20 mcg); upper safe limit 4000 IU/day

Upper Tolerable Limit

4000 IU/day (100 mcg) for adults; 1000-3000 IU/day for children depending on age

Absorption Enhancers

Dietary fat (increases micellar solubilization); magnesium (cofactor for vitamin D metabolism); bile acids

Absorption Inhibitors

Orlistat (blocks fat absorption, reducing vitamin D uptake); cholestyramine and colestipol (bile acid sequestrants); high-dose calcium supplements taken simultaneously

Side Effects

Possible Side Effects

Generally well-tolerated at 1000 IU/day; excessive doses may cause hypercalcemia, nausea, vomiting, constipation, polyuria, weakness, and kidney stones

Toxicity Risk

Low

Upper Tolerable Limit

4000 IU/day (100 mcg) for adults; 1000-3000 IU/day for children depending on age

Safety & Warnings

Contraindications

Hypercalcemia; hypervitaminosis D; hypersensitivity to cholecalciferol/excipients (and avoid/use only with specialist supervision in conditions predisposing to hypercalcemia such as granulomatous disease/sarcoidosis, severe renal impairment, or history of nephrolithiasis).

Pregnancy Safety

Consult Doctor

Children Suitability

Suitable for children; dose should be adjusted by age - consult a healthcare provider for pediatric dosing

Interactions

Medication Interactions

Orlistat and cholestyramine reduce absorption; thiazide diuretics increase hypercalcemia risk; corticosteroids impair vitamin D metabolism; anticonvulsants (phenytoin, phenobarbital) accelerate vitamin D catabolism

Supplement Interactions

High-dose calcium supplements may increase hypercalcemia risk when combined; magnesium deficiency impairs vitamin D activation

Special Populations

Target Population

Adults with limited sun exposure, elderly individuals (>65 years), dark-skinned individuals, people with malabsorption disorders, pregnant and breastfeeding women, individuals with osteoporosis risk

Children Suitability

Suitable for children; dose should be adjusted by age - consult a healthcare provider for pediatric dosing

Pregnancy Safety

Consult Doctor

Storage & Patient Advice

SFDA Storage Conditions

store below 25°c

Patient Counseling

Take 1 capsule (1000 IU) orally as directed; taking with a meal (preferably containing some fat) can improve absorption. Do not exceed the labeled/recommended dose without medical advice (typical adult tolerable upper intake level is 4000 IU/day). Consider checking serum 25‑OH vitamin D if long-term use, deficiency risk, or high-dose supplementation is planned. Consult a clinician before use if you have hypercalcemia, a history of kidney stones/severe renal impairment, or granulomatous disease (e.g., sarcoidosis) due to increased risk of vitamin D-related hypercalcemia.

Science & Evidence

Bioavailability Form

Vitamin D3 (cholecalciferol) is more effective at raising and sustaining blood vitamin D levels compared to Vitamin D2 (ergocalciferol).

Water or Fat Soluble

Fat-soluble

Scientific Evidence Level

Strong

Onset Timeline

Blood levels typically improve in 8-12 weeks, with bone health benefits observed after 3-6 months of consistent use.

Food Sources

Fatty fish (salmon, mackerel, sardines), cod liver oil, egg yolks, beef liver, UV-exposed mushrooms, fortified milk and cereals

Product Information

Supplement Type

Vitamin

Certification

SFDA registered (Registration No. 1703245054); GMP manufactured by Arnet Pharmaceutical Corp (USA)

Suitable for Vegans

No

Vitamin D Form

D3

Calcium Included

No

Vitamin K Included

No