Frequently bought together

Brand : DAFLON

DAFLON 500/MG FC TAB 30/FC TAB

Sku : I-001481
Key features
Daflon 500 mg is a prescription film-coated tablet containing diosmin 450 mg and hesperidin 50 mg. It acts as a venotonic and vasoprotective agent by improving venous tone, reducing capillary permeability, and supporting lymphatic drainage. It is used for the symptomatic treatment of chronic venous insufficiency, such as heavy or painful legs, and for acute hemorrhoidal attacks. It is supplied as 30 film-coated tablets.
- Brand: DAFLON
- Active Ingredient: DIOSMIN 450mg, HESPERIDIN 50mg
- Strength: 450,50mg
- Dosage Form: Film-coated tablet
- Pack Size: 30 Tablets
- Route: Oral use
- Prescription Status: Prescription
- Therapeutic Class: Cardiovascular
- Drug Class: Venotonic and vasoprotective agent; micronized purified flavonoid fraction (MPFF: diosmin + hesperidin).
- Manufacturer: LES LABORATOIRES SERVIER INDUSTRIE
- Country of Origin: France
- SFDA Registration No.: 2807257866
- Shelf Life: 36 months
- Storage: store below 30°c
- Formulation: Oral
- Contains Steroid: No

Frequently bought together

Description

Specification

Indications

Approved Uses

Symptomatic treatment of venolymphatic (chronic venous) insufficiency (e.g., heavy/painful legs) and symptomatic treatment of acute hemorrhoidal attack.

Off-Label Uses

Off-label/adjunct uses reported: venous leg ulcers (adjunct to compression), lymphedema (adjunct), and other microcirculatory disorders (e.g., diabetic retinopathy) where used in some settings but not universally guideline-endorsed.

Dosage & Administration

Dosing by Condition

Venolymphatic (chronic venous) insufficiency: 2 tablets/day with meals (e.g., 1 at midday and 1 in the evening). Acute hemorrhoidal attack: 6 tablets/day for 4 days, then 4 tablets/day for 3 days, taken with meals in divided doses.

Initial Dose

Acute hemorrhoidal attack: 6 tablets (3000mg) per day for the first 4 days.

Maintenance Dose

Venolymphatic insufficiency: 2 tablets (1000mg) per day.

Maximum Dose

6 tablets per day (3000mg total) during acute hemorrhoidal attack phase only

Pharmacology

Mechanism of Action

Improves venous tone and reduces venous capacitance/stasis; decreases capillary permeability and increases resistance; enhances lymphatic drainage; exerts anti-inflammatory microcirculatory effects (e.g., reduced leukocyte activation/mediators).

Onset of Action

Hemorrhoidal symptoms may improve within a few days on the acute regimen; for chronic venous insufficiency, symptom improvement typically requires ~2-4 weeks of continuous therapy and is maintained with ongoing daily dosing.

Bioavailability

Micronized purified flavonoid fraction (MPFF) improves oral absorption/bioavailability versus non‑micronized diosmin; absolute bioavailability is not well established.