JP VALERIAN 250/MG SG CAP 30/SG CAP

Benefits & Uses

Primary Benefit

Promotes relaxation and improves sleep quality by reducing the time to fall asleep and enhancing sleep duration.

Health Claims

Supports sleep onset and sleep quality; promotes relaxation and reduces mild anxiety-related restlessness; traditionally used as a mild sedative and anxiolytic

Common Deficiency Symptoms

Not applicable - valerian is not an essential nutrient; target symptoms include insomnia, difficulty falling asleep, restlessness, and anxiety-related sleep disturbance

Target Population

Adults experiencing mild to moderate insomnia or sleep disturbances, particularly those related to stress and nervous tension.

Scientific Evidence Level

Moderate

Onset Timeline

Acute effects on sleep onset may occur within 30-60 minutes; consistent improvement in sleep quality typically observed after 2-4 weeks of nightly use

Usage & Dosage

Suggested Use

Take 1 softgel capsule daily, 30-60 minutes before bedtime

Serving Size

1 Softgel Capsule

Servings Per Container

30

Best Time to Take

Before bed

Recommended Daily Intake

Adults: 300-900mg of valerian root extract taken 30-60 minutes before bedtime; no established RDA

Upper Tolerable Limit

No established UL; clinical studies have used up to 900mg/day for short-term use without significant adverse effects

Side Effects

Possible Side Effects

Generally well-tolerated at recommended doses; possible side effects include morning drowsiness, headache, dizziness, gastrointestinal upset, and vivid dreams; paradoxical stimulation reported in some individuals

Toxicity Risk

Low

Upper Tolerable Limit

No established UL; clinical studies have used up to 900mg/day for short-term use without significant adverse effects

Safety & Warnings

Contraindications

Known hypersensitivity to valerian (Valeriana officinalis/Valerianaceae) or any product component; pregnancy or breastfeeding (avoid due to insufficient safety data).

Pregnancy Safety

Avoid

Breastfeeding Safety

Avoid

Children Suitability

Not recommended under 18 years of age

Interactions

Medication Interactions

May potentiate CNS depressants including benzodiazepines, barbiturates, and sedative-hypnotics; may interact with CYP3A4-metabolized drugs; caution with anticoagulants

Supplement Interactions

Additive sedative effects when combined with melatonin, kava, passionflower, lemon balm, or 5-HTP; avoid concurrent use with high-dose magnesium glycinate for sedation stacking

Synergistic Nutrients

Lemon balm (Melissa officinalis), passionflower, magnesium glycinate, and melatonin - commonly combined for enhanced sleep support

Special Populations

Target Population

Adults experiencing mild to moderate insomnia or sleep disturbances, particularly those related to stress and nervous tension.

Children Suitability

Not recommended under 18 years of age

Pregnancy Safety

Avoid

Breastfeeding Safety

Avoid

Storage & Patient Advice

SFDA Storage Conditions

store below 25°c

Patient Counseling

Take 1 softgel orally 30-120 minutes before bedtime (or as directed on the label). May cause drowsiness-do not drive or operate machinery after taking. Avoid alcohol and other CNS depressants/sedatives. Use short-term; if insomnia persists or you need use beyond ~2-4 weeks, seek medical advice. Avoid use in pregnancy or breastfeeding unless advised by a clinician; not recommended for children/adolescents without medical advice.

Science & Evidence

Bioavailability Form

Natural valerian root extract; the combined effect of multiple compounds is believed to contribute to its efficacy.

Scientific Evidence Level

Moderate

Onset Timeline

Acute effects on sleep onset may occur within 30-60 minutes; consistent improvement in sleep quality typically observed after 2-4 weeks of nightly use

Food Sources

Valerian root is not a dietary food source; it is exclusively available as a herbal supplement or tea

Product Information

Supplement Type

Herbal

Certification

SFDA registered (Registration No. 1812234594); manufactured under GMP by Jamjoom Pharmaceuticals Factory Company, Saudi Arabia

Active Mechanism

GABA modulator - valerenic acid inhibits GABA-A receptor degradation and acts as a partial agonist at GABA-A receptors, increasing GABAergic tone and promoting sedation; additionally modulates adenosine A1 receptors and serotonin 5-HT5a receptors to reduce sleep latency

Habit Forming

Low risk