BILOBIL 80 MG 60 CAPS

Benefits & Uses

Primary Benefit

Supports cognitive function, memory, and cerebral blood circulation by improving microvascular blood flow to the brain.

Health Claims

Supports cognitive function and memory in age-related cognitive decline; improves symptoms of cerebral insufficiency including poor concentration and tinnitus; enhances peripheral and cerebral microcirculation; provides antioxidant protection via flavonoid glycoside content.

Common Deficiency Symptoms

Not applicable - Ginkgo biloba is not an essential nutrient. It is used therapeutically to address symptoms such as diminished memory, difficulty concentrating, tinnitus, and suboptimal peripheral circulation.

Target Population

Adults over 50 experiencing age-related cognitive decline; individuals with mild memory impairment; patients with peripheral vascular insufficiency; adults with tinnitus or vertigo of vascular origin.

Scientific Evidence Level

Moderate

Onset Timeline

Initial effects on circulation may be noticed within 2-4 weeks; cognitive and memory benefits typically require 8-12 weeks of consistent use.

Usage & Dosage

Suggested Use

Take 1 capsule twice daily with water, preferably with meals.

Serving Size

1 capsule (84mg Ginkgo biloba extract EGb 761)

Servings Per Container

60

Recommended Daily Intake

Adults: 120-240 mg/day of dry extract of Ginkgo biloba folium (EGb 761), divided into 2-3 doses

Upper Tolerable Limit

240mg/day of standardized extract; doses above 240mg/day are not associated with additional benefit and increase risk of adverse effects.

Absorption Enhancers

Taking with food improves tolerability and may slightly enhance absorption; consistent daily dosing maintains steady plasma levels.

Side Effects

Possible Side Effects

Headache, dizziness, gastrointestinal upset (nausea, diarrhea), allergic skin reactions; increased bleeding risk at higher doses; rare cases of seizures reported in predisposed individuals.

Toxicity Risk

Low

Upper Tolerable Limit

240mg/day of standardized extract; doses above 240mg/day are not associated with additional benefit and increase risk of adverse effects.

Safety & Warnings

Contraindications

Hypersensitivity to Ginkgo biloba (ginkgo leaf) or any excipients; pregnancy and breastfeeding (avoid due to insufficient safety data); bleeding disorders or concomitant anticoagulant/antiplatelet therapy (avoid or use only with medical supervision due to bleeding risk); discontinue prior to surgery/invasive procedures (typically at least 1-2 weeks before, per perioperative herbal guidance); seizure disorders/epilepsy (avoid due to potential pro-convulsant risk).

Pregnancy Safety

Avoid

Breastfeeding Safety

Avoid

Children Suitability

Not recommended under 18 years of age.

Interactions

Medication Interactions

Significantly increases bleeding risk when combined with anticoagulants (warfarin, heparin) and antiplatelet drugs (aspirin, clopidogrel); may reduce efficacy of anticonvulsants (phenytoin, valproate); may interact with SSRIs increasing serotonin syndrome risk; may alter metabolism of drugs via CYP2C19 and CYP3A4 pathways; may interact with diabetes medications, statins, and HIV drugs such as efavirenz.

Supplement Interactions

Additive bleeding risk with fish oil (omega-3), vitamin E, garlic, and ginger supplements; avoid combining with other herbal anticoagulants such as feverfew or dong quai.

Special Populations

Target Population

Adults over 50 experiencing age-related cognitive decline; individuals with mild memory impairment; patients with peripheral vascular insufficiency; adults with tinnitus or vertigo of vascular origin.

Children Suitability

Not recommended under 18 years of age.

Pregnancy Safety

Avoid

Breastfeeding Safety

Avoid

Storage & Patient Advice

SFDA Storage Conditions

store below 25°c

Storage Conditions

Store below 25°C in the original blister pack; protect from moisture and direct sunlight; keep out of reach of children.

Patient Counseling

BILOBIL FORTE (Ginkgo leaf extract) 80 mg capsule: Take 1 capsule twice daily by mouth; may be taken with or without food (taking with meals can reduce GI upset). Use consistently; assess benefit after ~8-12 weeks. Do not exceed the labeled daily dose. Inform your doctor/pharmacist before use if you are pregnant, breastfeeding, taking anticoagulants/antiplatelets, or have bleeding disorders.

Science & Evidence

Bioavailability Form

Standardized dry extract EGb 761 - standardization to 24% flavone glycosides and 6% terpene lactones ensures consistent potency and reproducible clinical effects; terpene lactones (ginkgolides, bilobalide) are well-absorbed with bioavailability up to 80%.

Scientific Evidence Level

Moderate

Onset Timeline

Initial effects on circulation may be noticed within 2-4 weeks; cognitive and memory benefits typically require 8-12 weeks of consistent use.

Food Sources

Ginkgo biloba is not found in common dietary foods; the therapeutic extract is derived exclusively from the leaves of the Ginkgo biloba tree.

Product Information

Supplement Type

Herbal

Allergen Info

No common allergens (gluten-free, dairy-free, soy-free); capsule shell is typically made from hydroxypropyl methylcellulose (HPMC); may cause allergic skin reactions in sensitive individuals.

Certification

SFDA registered (Registration No. 207245467); manufactured by KRKA d.d., Novo Mesto, Slovenia under GMP-certified conditions.

Plant Source

Ginkgo (Ginkgo biloba)

Standardized Extract

Standardized to 24% ginkgo flavone glycosides (20.16mg) and 6% terpene lactones (5.04mg) per 84mg EGb 761 extract