CO-Q10 100/MG SG CAP 30/CAP

Benefits & Uses

Primary Benefit

Supports cellular energy production (ATP synthesis) and acts as a potent antioxidant, benefiting cardiovascular and mitochondrial function.

Health Claims

Supports mitochondrial energy production (ATP synthesis); provides antioxidant protection against oxidative stress; supports cardiovascular health; may reduce statin-associated myopathy symptoms.

Common Deficiency Symptoms

Fatigue, muscle weakness, exercise intolerance, cognitive decline, increased oxidative stress, and in severe cases, heart failure symptoms.

Target Population

Adults over 40, patients on statin therapy, individuals with cardiovascular conditions, people with chronic fatigue, athletes seeking performance support, and those with mitochondrial disorders.

Scientific Evidence Level

Moderate

Usage & Dosage

Suggested Use

Take 1 softgel capsule daily with a meal containing fat.

Serving Size

1 softgel capsule

Servings Per Container

30

Best Time to Take

Morning / With meals

Recommended Daily Intake

Adults: 100-200mg/day for general health; 300-600mg/day for therapeutic use (no official RDA established).

Upper Tolerable Limit

No established UL; doses up to 1200mg/day have been used in clinical studies without significant toxicity.

Absorption Enhancers

Take with a fat-containing meal (e.g., avocado, nuts, olive oil); piperine (black pepper extract) may enhance absorption; dividing doses improves uptake at higher doses.

Absorption Inhibitors

High-fiber meals may reduce absorption; statins reduce endogenous CoQ10 synthesis; taking on an empty stomach reduces bioavailability.

Side Effects

Possible Side Effects

Generally well-tolerated at recommended doses; high doses may cause mild gastrointestinal discomfort, nausea, diarrhea, loss of appetite, or insomnia when taken late in the day.

Toxicity Risk

Low

Upper Tolerable Limit

No established UL; doses up to 1200mg/day have been used in clinical studies without significant toxicity.

Safety & Warnings

Contraindications

Known hypersensitivity to ubidecarenone (Coenzyme Q10) or any excipients; use with caution in patients receiving anticoagulant therapy (e.g., warfarin) due to potential reduction in anticoagulant effect.

Children Suitability

Not recommended for children without medical supervision; no established pediatric dosing for this product.

Interactions

Medication Interactions

May reduce the anticoagulant effect of warfarin (monitor INR); statins deplete endogenous CoQ10 levels; may have additive blood pressure-lowering effects with antihypertensives; may interact with certain chemotherapy agents.

Supplement Interactions

May have additive antioxidant effects with Vitamin E and Vitamin C; concurrent use with red yeast rice may further deplete endogenous CoQ10.

Special Populations

Target Population

Adults over 40, patients on statin therapy, individuals with cardiovascular conditions, people with chronic fatigue, athletes seeking performance support, and those with mitochondrial disorders.

Children Suitability

Not recommended for children without medical supervision; no established pediatric dosing for this product.

Storage & Patient Advice

SFDA Storage Conditions

do not store above 30°c

Storage Conditions

Store below 30°C in a cool, dry place. Keep away from direct sunlight and moisture. Keep out of reach of children.

Patient Counseling

Take 1 softgel capsule (100 mg) orally once daily with food, preferably a meal containing fat, to improve absorption and reduce gastrointestinal upset; avoid taking on an empty stomach. If you take warfarin or other vitamin K-antagonist anticoagulants, consult your clinician and monitor INR because coenzyme Q10 (ubidecarenone) may reduce anticoagulant effect. Do not exceed the recommended dose without medical advice. Store below 30°C.

Science & Evidence

Bioavailability Form

Ubidecarenone (oxidized CoQ10) in oil-based softgel form - fat-soluble delivery significantly enhances absorption compared to dry powder capsules; the body can partially convert ubidecarenone to the more bioavailable ubiquinol form.

Water or Fat Soluble

Fat-soluble

Scientific Evidence Level

Moderate

Food Sources

Organ meats (heart, liver, kidney), beef, sardines, mackerel, pork, chicken, spinach, broccoli, cauliflower, peanuts, soybeans.

Product Information

Supplement Type

Coenzyme

Allergen Info

Contains gelatin (softgel capsule, likely bovine or porcine origin); free from gluten; soy and other allergens not specified on label.

Certification

SFDA registered (Reg. No. 12-1122-2012); manufactured by Jamjoom Pharmaceuticals Factory Company under GMP standards.

Suitable for Vegetarians

Check product-specific information; softgel capsules often contain gelatin.

Suitable for Vegans

Check product-specific information; softgel capsules often contain gelatin.